Reversible hemiparesis associated with the use of topiramate
نویسندگان
چکیده
We report a case of a 5-year-old boy with intractable partial seizures who developed a transient hemiparesis, worsening of the electroencephalogram (EEG) and a change in his seizure pattern with increased seizure frequency after receiving topiramate (TPM). Symptoms resolved within a month after TPM was discontinued. Clinicians need to be aware that TPM use may occasionally be associated with focal motor weakness and exacerbation of seizures.
منابع مشابه
Probable topiramate-induced hemiparesis.
Topiramate is a broad-spectrum antiepileptic medication that is used as monotherapy or in combination with other medications to treat epilepsy in both adults and children. It is also indicated for migraine prophylaxis in adults. An off-label use of topiramate is as a mood stabilizer (with no associated weight gain) in rapid-cycling and mixed bipolar episodes. The mechanisms of action of topiram...
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ورودعنوان ژورنال:
- Seizure
دوره 11 شماره
صفحات -
تاریخ انتشار 2002